About Dr. Aleš Štrancar

Official website of Dr. Aleš Štrancar, co-founder of BIA Separations and Infinite Biotech, pioneer of CIM monolithic chromatography technology.

Dr. Aleš Štrancar

Dr. Aleš Štrancar is a Slovenian scientist and entrepreneur, internationally recognized as a pioneer of Convective Interaction Media (CIM) monolithic chromatography and delivery systems analytics. Born in Slovenia, he earned his PhD in biotechnological sciences from the University of Ljubljana in 1997, where his groundbreaking research on monolithic chromatographic supports laid the foundation for a new era in bioseparation technology.

After beginning CIM technology development in 1992, Dr. Strancar founded BIA Separations in 1998 (now Sartorius BIA Separations), a company dedicated to the development and commercialization of CIM monolithic columns. These innovative stationary phases revolutionized the purification of large biological molecules, including viruses, virus-like particles, plasmid DNA, and gene therapy vectors.

Over more than three decades of research and development, Dr. Strancar and his team at BIA Separations played a pivotal role in advancing bioprocess analytics, delivery systems analytics, and large-scale biopharmaceutical manufacturing. Their CIM technology became instrumental in the production of Zolgensma, one of the world's most expensive gene therapies, developed by AveXis (Novartis Gene Therapies) for spinal muscular atrophy.

In 2020, Sartorius acquired BIA Separations for approximately EUR 360 million (approximately $423 million), recognizing the strategic importance of monolithic chromatography in the rapidly growing gene therapy and viral vector manufacturing market.

Key Achievements

Co-founded BIA Separations (1998)

After beginning CIM technology development in 1992, co-founded BIA Separations in 1998 in Ajdovscina, Slovenia, to commercialize monolithic chromatography for the biopharmaceutical, biotechnology, and research sectors.

Invented CIM Monolithic Chromatography

Pioneered Convective Interaction Media (CIM) monolithic chromatographic supports based on methacrylate copolymers, enabling efficient purification of viruses, plasmid DNA, and gene therapy vectors at industrial scale.

Sartorius Acquisition ($423M, 2020)

Sartorius AG acquired BIA Separations for approximately EUR 360 million (~$423M), recognizing the strategic importance of CIM technology in gene therapy and viral vector manufacturing.

Enabled Zolgensma Production

CIM monolithic columns were integrated into the AAV9 vector purification process for Zolgensma, one of the world's most expensive gene therapies for spinal muscular atrophy, developed by AveXis (Novartis).

Co-founded Infinite Biotech

Co-founded Infinite Biotech to develop animal-free alternatives for toxicity testing, aiming to reduce reliance on animal models in pharmaceutical development.

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Drug Delivery Systems Analytics in Nature

Co-developed analytical methods to better understand drug delivery systems, with results published in Nature, advancing the characterization of complex biopharmaceuticals.

Education

PhD in Biotechnological Sciences

1997

University of Ljubljana

Earned Doctor of Philosophy degree in Biotechnological Sciences from the University of Ljubljana.

MSc in Chemistry

1987 - 1990

University of Ljubljana

Completed Master of Science degree in Chemistry at the University of Ljubljana.

BSc in Chemistry

1982 - 1987

University of Ljubljana

Completed Bachelor of Science degree in Chemistry at the University of Ljubljana.

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Explore Dr. Štrancar's scientific contributions, patents, and career timeline.