US12533607B2

Multimodal metal affinity processing of AAV capsids

Inventors: Aleš Štrancar
Filed: August 18, 2021Granted: January 27, 2026

A method for separating full adeno-associated virus (AAV) capsids from empty AAV capsids in a buffered mixture comprising full AAV capsids and empty AAV capsids, comprising the steps of contacting the...

US10570376B2

Method for influenza virus purification

Inventors: Aleš Štrancar
Filed: July 6, 2015Granted: February 25, 2020

A process for the purification of influenza virus or derivative thereof requires providing a source of influenza virus or derivative thereof, optionally subjecting the source to a pre-purification ste...

ATE276357T1

Purification of vitamin-K dependent proteins by membrane chromatography

Inventors: Djuro Josić ; Aleš Štrancar
Filed: December 7, 1994Granted: October 15, 2004

A process for preparing agents containing virus-inactivated vitamin K-dependent plasma components as well as protein C, protein S, factors II, VII, IX and/or X as well as combinations thereof, such as...

US6736973B1

Novel chromatographic device

Inventors: Aleš Podgornik ; Miloš Barut ; Aleš Štrancar ; Djuro Josić
Filed: February 27, 1999Granted: May 18, 2004

A porous self-supporting structure comprising at least two porous components A and B and the porous component B embraces the porous component A, wherein surfaces of pores of the at least two porous co...

US20230302381A1

Metal-affinity extraction of host cell DNA

Inventors: Aleš Štrancar
Filed: August 18, 2021

A method for removal of host cell DNA from a sample containing a species of desired protein, virus, or extracellular vesicle comprising the steps of loading a substrate bearing an anionic metal affini...

EP3707250A1

SO3 chromatography for use in a method for virus purification

Inventors: Aleš Štrancar
Filed: November 8, 2018

The present invention refers to a process for purifying virus particles from cell culture, comprising the steps of subjecting the cell culture to centrifugation to get a supernatant fraction of virus ...

SI1711468T1

Process for preparing purified ciprofloxacin

Inventors: Aleš Štrancar
Filed: February 1, 2005

A process for purifying ciprofloxacin is described wherein a solution of ciprofloxacin is contacted with a solid phase for chromatographic purification.

WO2002000337A1

Chromatography material and a process of manufacturing that material

Inventors: Alois Jungbauer ; Rainer Hahn ; Aleš Podgornik ; Miloš Barut ; Aleš Štrancar
Filed: June 27, 2001

A process of manufacturing of a chromatography material comprising the steps of reacting a polymerisable at least bifunctional monomer A with a ligand also having a functional group which binds covale...

WO1996006158A1

Device for the rapid separation and/or conversion of substrates

Inventors: Djuro Josić ; Primož Koselj ; Aleš Podgornik ; Aleš Štrancar
Filed: August 22, 1995

A process for the conversion of substrates both for analytical and preparative purposes in a flow-through and cross-flow reactor having compact porous discs and/or compact porous tubes as carrier for ...

Ohišje za porozne diske

Inventors: Aleš Štrancar ; Miloš Barut ; Aleš Podgornik ; Djuro Josić

Ohišje za porozne cevne module

Inventors: Aleš Štrancar ; Miloš Barut ; Aleš Podgornik ; Djuro Josić

Konstrukcija cevnega modula večjih volumnov

Inventors: Aleš Podgornik ; Miloš Barut ; Aleš Štrancar ; Djuro Josić